Anti Asthmatic
Mostrando 1-12 de 37 artigos, teses e dissertações.
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1. Tangeretin has anti-asthmatic effects via regulating PI3K and Notch signaling and modulating Th1/Th2/Th17 cytokine balance in neonatal asthmatic mice
Asthma is a chronic allergic disease characterized by airway inflammation, airway hyper-responsiveness (AHR), and mucus hypersecretion. T-lymphocytes are involved in the pathogenesis of asthma, mediating airway inflammatory reactions by secreting cytokines. The phosphoinositide 3-kinase (PI3K) and Notch signaling pathways are associated with T cell signaling
Braz J Med Biol Res. Publicado em: 20/07/2017
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2. GABAergic effect of valeric acid from Valeriana wallichii in amelioration of ICV STZ induced dementia in rats
ABSTRACT Valeriana wallichii DC., Caprifoliaceae, is used to have anti-ulcer, anti-spasmodic, anti-epileptic, memory enhancer, anti-anxiety, anti-rheumatic, sedative, anti-asthmatic and diuretic activities. V. wallichii is reported to contain valpotriates, valeric acid, valerenic acid, valechlorine, valerianine, resins and alkaloids. Valeric acid, found in V
Rev. bras. farmacogn.. Publicado em: 2016-08
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3. Stereoselective total synthesis of the potent anti-asthmatic compound CMI-977 (LDP-977)
Neste trabalho, uma síntese curta e eficiente para o CMI-977 (LDP-977), um potente agente antiasmático oralmente ativo, é descrita. As etapas chave envolveram uma ciclização oxidativa de Mukaiyama, fornecendo a unidade trans-THF (tetrahidrofurano) e uma reação de homologação de Seyferth-Gilbert para construção da tripla ligação da molécula alvo
J. Braz. Chem. Soc.. Publicado em: 2013-02
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4. Efeitos do treinamento físico aeróbico de baixa intensidade na inflamação alérgica crônica e na resposta imune de camundongos sensibilizados / Effects of the aerobic physical training of decrease intensity in the chronic allergic inflammation and in the immune response of mice sensitized
The physical training (PT) is part of the pulmonary rehabilitation of asthmatic patients and seems to reduce the number of crises, the use of medicine, the broncoespasm prompted by the exercise and increase the tolerance to the effort and the quality of life. Despite of these benefits, a few studies have investigated possible anti-inflammatory effects trigge
Publicado em: 2009
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5. Cordicoterapia oral e inflamatória para o tratamento de sibilancia na infância : uso e abuso
The systemic and topical therapy with corticosteroids for asthma treatment is a consensual point in the literature and an important topic in the guidelines on disorder management. Currently, it is the medication with the best results in asthma control, with quick symptoms reduction, significant improvement in inflammation and pulmonary function. Moreover, it
Publicado em: 2009
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6. Acanthospermum hispidum DC (Asteraceae): validaÃÃo para fins farmacÃuticos
Acanthospermum hispidum tem suas raÃzes empregadas no tratamento da asma, fazendo parte da formulaÃÃo de um xarope, prescrito como antiasmÃtico, nos postos de saÃde da Prefeitura de Olinda, desde o final da dÃcada de 80. O rÃpido sucesso do produto apontou para a necessidade de aprofundamento dos conhecimentos sobre esta espÃcie vegetal. Atualmente,
Publicado em: 2007
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7. Local anaesthetic medication for the treatment of asthma
It is presumed that drugs able to prevent bronchial spasm and/or inflammation may have therapeutic potential to control asthma symptoms. The local anaesthetic lidocaine has recently received increased attention as an alternative form of treatment for asthmatic patients. This paper reviews the major findings on the topic and summarizes the putative mechanisms
Memórias do Instituto Oswaldo Cruz. Publicado em: 2005-03
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8. Evaluation of immune response of asthmatic individuals living in an endemic area of Schistosoma mansoni. / Avaliação da resposta imune de indivíduos asmáticos residentes em área endêmica em Schistosoma mansoni.
A prevalência de infecção por helmintos é negativamente associada à prevalência de alergia, e alguns trabalhos têm demonstrado uma inversa associação entre infecções por helmintos e gravidade de asma. Neste trabalho, foi avaliada a resposta imune específica para alérgeno 1 de Dermatophagoides pteronyssinus (Der p 1) em asmáticos infectados com
Publicado em: 2005
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9. Increase in numbers of CD8 positive lymphocytes and eosinophils in peripheral blood of subjects with late asthmatic reactions induced by toluene diisocyanate.
Occupational asthma induced by toluene diisocyanate (TDI) shares several features with allergic asthma, but the mechanism of action of TDI is poorly understood. Ten sensitised subjects, previously shown to develop a dual or late asthmatic reaction after inhaling TDI were examined. In each subject, forced expiratory volume in one second (FEV1) was measured an
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10. Platelet kinetics in asthmatic patients with and without aspirin intolerance.
BACKGROUND: A reduced platelet survival time has been described in asthmatic patients. There is also good evidence that platelets are involved in aspirin induced asthma. Since aspirin intolerant patients usually suffer from an active disease and often require anti-inflammatory treatment, it has been suggested that platelet survival time may be shorter in asp
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11. Involvement of immunoglobulin E in the secretory processes of alveolar macrophages from asthmatic patients.
Alveolar macrophages from nonatopic donors were passively sensitized with allergen-specific IgE antibody from the serum of asthmatic patients. A selective release of 4-8% of the lysosomal beta-glucuronidase of these cells occurred within 30 min of contact with the related allergen or with anti-human IgE antibody, in the absence of any mast or basophil cells.
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12. Autologously up-regulated Fc receptor expression and action in airway smooth muscle mediates its altered responsiveness in the atopic asthmatic sensitized state
To elucidate the role of IgE-dependent mechanisms in inducing altered airway responsiveness in the atopic asthmatic state, the expression and actions of Fc receptor activation were examined in isolated rabbit tracheal smooth muscle (TSM) tissue and cultured cells passively sensitized with sera from atopic asthmatic patients or nonatopic/nonasthmatic (control
The National Academy of Sciences.