Animal Carcinogenesis
Mostrando 1-12 de 37 artigos, teses e dissertações.
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1. Phytotoxins eliminated by milk: a review
RESUMO: O leite é uma mistura complexa de lipídeos suspensos em solução aquosa de proteínas e pode ser veículo de diversos contaminantes, mas, geralmente, não é uma importante via de excreção de tóxicos. O principal problema é a exposição repetida, como ocorre com a ingestão de plantas tóxicas, e seu potencial perigo para os animais que conso
Pesq. Vet. Bras.. Publicado em: 02/05/2019
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2. Efeito da dieta à base de Cogumelo do Sol (Agaricus blazei, Murrill) no parênquima pulmonar de ratos submetidos a estímulo carcinogênico pela nitrosamina 4-metilnitrosamina-1-3piridil-1 butanona (NNK) / Effect of diet of sun mushroom (Agaricus blazei Murrill) in the lung parenchyma of rats subjected to stimulation with the carcinogen nitrosamine-4-1-metilnitrosamine 3piridil-1butanone (NNK)
The mushrooms have been used for many years as food for its nutritional value and/or as a therapeutic agent. One of the most studied fungus is currently the Agaricus blazei Murrill, popularly Known as Cogumelo do Sol, for its beneficial credited in the prevention of cancer. This study examined the effects of ingestion of A. blazei in the lung parenchyma of w
Publicado em: 2010
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3. AvaliaÃÃo da aÃÃo da laserterapia nÃo cirÃrgica em modelo experimental induzido por cacinÃgeno quÃmico
Low energy laser promotes therapeutic effects and morfodifferentiation and cell proliferation alterations. Its action in the proliferative activity is a controversial subject because studies show inhibition, proliferation or indifference regarding the cellular growth. In fact, the proliferation of normal and tumoral cells can be stimulated, but this process
Publicado em: 2009
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4. L-arginine administration : the effect on myocardial fibrosis and increase of the carcinogenesis in mice mdx / Administração de L-arginina : efeitos sobre a fibrose miocardica e aumento da carcinogenese em camundongos mdx
The Duchenne Muscle Dystrophy (DMD) is a myopathy characterized by dystrophin absence, which is a structural protein of the plasma membrane. The dystrophin absence leads to functional alterations followed by necrosis in the skeletal and cardiac muscle fiber. As the patients grow older, about 40% of them develop cardiomyopathy due to progressive myocardial fi
Publicado em: 2009
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5. Evaluation of the tumor inhibitive effect of in natura (Copaifera reticulata) and hand prepared oil in the DMBA-induced oral carcinogenesis model / Avaliação do efeito inibidor tumoral do óleo resina de copaíba in natura (Copaifera reticulata) e manipulado artesanalmente no modelo de carcinogênese bucal experimental DMBA induzida
A Medicina natural tem se apresentado como alternativa para a cura de inúmeras doenças que afetam a população, utilizando-se de plantas da flora brasileira; muito embora ainda não sejam totalmente esclarecidos os princípios ativos, mecanismo de ação e características de citotoxicidade destes produtos. Uma dessas substâncias é um óleo extraído de
Publicado em: 2007
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6. Trypanosoma cruzi infection and/or administration of the nonsteroidal anti-inflammatory nimesulide increase the number of colonic crypts overexpressing metallothioneins in rat colon carcinogenesis
Trypanosoma cruzi infection and nonsteroidal anti-inflammatory drugs inhibit colorectal carcinogenesis by mechanisms not completely known and metallothionein proteins (MTs) may be involved in this process. Sixty-six male Wistar rats weighing 90 to 120 g were randomly divided into seven groups (GI to GVII). GI, GII and GIII animals were subcutaneously infecte
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-07
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7. Carcinogênese pulmonar em camundongos portadores de deleção em um dos alelos do gene da Cx43 / Lung carcinogenesis in mice with a deletion in one allele of Cx43 gene
Gap junctions are communicating protein channels formed between adjacent cells that allow the exchange of molecules and ions smaller than 1kDa; connexins are proteins that form these junctions. Studies in the literature have been showing the lower level of cell communication capacity and alterations in the expression and/or localization of connexins in neopl
Publicado em: 2005
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8. Espectroscopia de fluorescência na detecção de lesões quimicamente induzidas por agente carcinogênico na borda lateral da língua-estudo in vivo / Fluorescence spectroscopy to detection of chemically induced lesion at the lateral vorder of the tongue - in vivo study.
The diagnostic validity of the fluorescence spectroscopy in the discrimination of induced lesions at lateral border of the tongue of hamsters was investigated in this study. The animal model using chemical induction with DMBA (dimethylbenzanthracene) was chosen for the carcinogenesis phases comparable to the ones observed at oral cancer development in humans
Publicado em: 2005
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9. Biological activities of Curcuma longa L.
There are several data in the literature indicating a great variety of pharmacological activities of Curcuma longa L. (Zingiberaceae), which exhibit anti-inflammatory, anti-human immunodeficiency virus, anti-bacteria, antioxidant effects and nematocidal activities. Curcumin is a major component in Curcuma longa L., being responsible for its biological action
Memórias do Instituto Oswaldo Cruz. Publicado em: 2001-07
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10. Avaliação do efeito inibidor da vitamina C na carcinogenese esofagica experimental induzida pela dietilnitrosamina
Cancer is today the second death cause in developed countries. In spite of the fact that certain advances have been obtained in the course of its treatment, the prognosis of this disease is still far from being satisfactory. Although esophageal cancer is not among the most frequent kinds of cancer actually it is the fourth neoplasia to affect man s digestive
Publicado em: 1998
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11. Chemical carcinogenesis: too many rodent carcinogens.
The administration of chemicals at the maximum tolerated dose (MTD) in standard animal cancer tests is postulated to increase cell division (mitogenesis), which in turn increases rates of mutagenesis and thus carcinogenesis. The animal data are consistent with this mechanism, because a high proportion--about half--of all chemicals tested (whether natural or
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12. ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis
Despite the importance of epidermal growth factor receptor (EGFR) in animal development and malignant transformation, surprisingly little is known about the regulation of its expression. Here, we report a novel zinc finger and G-patch domain-containing protein, ZIP. We demonstrated that ZIP acts as a transcription repressor through the recruitment of the nuc
Nature Publishing Group.