Amerindians
Mostrando 13-24 de 64 artigos, teses e dissertações.
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13. Mitochondrial DNA mapping of social-biological interactions in Brazilian Amazonian African-descendant populations
The formation of the Brazilian Amazonian population has historically involved three main ethnic groups, Amerindian, African and European. This has resulted in genetic investigations having been carried out using classical polymorphisms and molecular markers. To better understand the genetic variability and the micro-evolutionary processes acting in human gro
Publicado em: 2010
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14. Vestígios do passado : a história ameríndia revelada através de marcadores genéticos
Este trabalho teve como meta principal contribuir para elucidar algumas das questões em aberto pertinentes à história evolutiva e antropológica de populações nativas americanas. Para isso investigou-se marcadores uniparentais paternos, ligados à NRY, e materno, mtDNA. Para o cromossomo Y foram investigados 108 indivíduos (85 sulameríndios de 16 trib
Publicado em: 2010
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15. DNA tests probe the genomic ancestry of Brazilians
We review studies from our laboratories using different molecular tools to characterize the ancestry of Brazilians in reference to their Amerindian, European and African roots. Initially we used uniparental DNA markers to investigate the contribution of distinct Y chromosome and mitochondrial DNA lineages to present-day populations. High levels of genetic ad
Brazilian Journal of Medical and Biological Research. Publicado em: 11/09/2009
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16. Haptoglobin gene subtypes in three Brazilian population groups of different ethnicities
Haptoglobin is a plasma hemoglobin-binding protein that limits iron loss during normal erythrocyte turnover and hemolysis, thereby preventing oxidative damage mediated by iron excess in the circulation. Haptoglobin polymorphism in humans, characterized by the Hp*1 and Hp*2 alleles, results in distinct phenotypes known as Hp1-1, Hp2-1 and Hp2-2, whose frequen
Genetics and Molecular Biology. Publicado em: 26/06/2009
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17. Analysis of the CCR5 gene coding region diversity in five South American populations reveals two new non-synonymous alleles in Amerindians and high CCR5*D32 frequency in Euro-Brazilians
The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The effect of the CCR5*D32 allele in susceptibility to HIV infection and AIDS disease is well known. Other alleles than CCR5*D32 have not been analysed before, neither in Amerindians nor in the majority of the populations all over the world. We investigated the distribution of t
Genetics and Molecular Biology. Publicado em: 16/01/2009
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18. Infecção pelo herpesvírus 8 humano (HHV-8) em populações indígenas e não indígenas da Amazônia brasileira / Human herpesvirus-8 infection in amerindian and non-amerindian populations in the brazilian Amazon region
Human herpes virus type 8 (HHV-8) is hyperendemic in Amerindian populations, but its modes of transmission are unknown. Objectives: 1. Study the Human Herpesvirus-8 Infection and Oral Shedding in Amerindian and Non-Amerindian Populations in the Brazilian Amazon Region. 2. Methods: Antibodies against either HHV-8 latency-associated nuclear antigen (LANA) or H
Publicado em: 2009
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19. Estudo epidemiológico da infecção por herpesvírus 8 humano (HHV-8) em população indígena da Amazônia brasileira / Epidemiological study of Human herpesvirus 8 infection (HHV-8) in the Amerindian population from Brazilian Amazon
The human herpesvirus 8 (HHV-8) is endemic in Africa and Amerindian populations from Amazon region. The infection in those populations occurs during childhood and, in Africa, involves a close contact in intrafamilial environment. Several studies confirm the geographical distribution of different subtypes of HHV-8, and the subtype E is typical of the Amerindi
Publicado em: 2009
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20. Genética de populações e reinterpretação da história demográfica de remanescentes de quilombos: uma comparação entre três populações do nordeste brasileiro
The remanescentes de quilombos are multiethnic societies whose origins are related to the presence of African slaves in Brazil. The demographic history of these populations has been studied using historical, demographic, ethnographic and genetic sources. The present work aims to evaluate the origin and the impact of recent and ancient waves of immigration up
Publicado em: 2009
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21. Polimorfismo e evolução do gene HLA-B nas Américas / Polymorphism and evolution of HLA-B gene in the Americas
Existem evidências de que o gene HLA-B, cujo produto tem como função a apresentação de peptídeos a linfócitos CD8+ e ligação a receptores KIR, esteja sob a ação da seleção natural. As populações nativas da América do Sul possuem uma grande quantidade de alelos de HLA-B exclusivos (endêmicos) em freqüências elevadas, enquanto que as popula�
Publicado em: 2009
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22. Absence of the -116A variant of the butyrylcholinesterase BCHE gene in Guarani Amerindians from Mato Grosso do Sul
Butyrylcholinesterase (BChE; EC 3.1.1.8; Online Mendelian Inheritance in Man (OMIM) number 177400) is an enzyme found in many human tissues and encoded by the BCHE gene, of which 65 variants have been identified. In a recent study we found that the -116A variant of exon 1 of the BCHE gene was associated with lower mean BChE activity. The present study analyz
Genetics and Molecular Biology. Publicado em: 2008
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23. Signatures of natural selection and non-selective process in the 5´cis regulatory region of CCR5 gene of Amerindians from Brazilian Amazonian region / Análise do polimorfismo da região cis-reguladora do gene CCR5 em populações ameríndias
Populações nativas da América do Sul apresentam diversidade genética reduzida em relação às demais populações do mundo e alta diferenciação interpopulacional dentro do continente. As pressões seletivas sobre a região cis-reguladora do CCR5 geram uma assinatura de diversidade oposta àquela esperada com base na história demográfica, reduzindo a
Publicado em: 2008
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24. Mitochondrial DNA mapping of social-biological interactions in Brazilian Amazonian African-descendant populations
The formation of the Brazilian Amazonian population has historically involved three main ethnic groups, Amerindian, African and European. This has resulted in genetic investigations having been carried out using classical polymorphisms and molecular markers. To better understand the genetic variability and the micro-evolutionary processes acting in human gro
Genetics and Molecular Biology. Publicado em: 2008