Alloimmunized
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Use of prophylactic phototherapy for RhD neonatal disease in a referral service
Abstract Objective: This study aimed to describe the effect of prophylactic phototherapy in the treatment of infants with Neonatal Hemolytic Disease. Method: A retrospective cohort study was carried out with 199 RhD-positive infants, born to RhD-negative mothers, alloimmunized for RhD antigen, between January 2009 and December 2018. Results: The incidence
Jornal de Pediatria. Publicado em: 2023
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2. Clinical and epidemiological profile of alloimmunized and autoimmunized multi-transfused patients against red blood cell antigens in a blood center of Minas Gerais
ABSTRACT Background: The large diversity of red blood cell antigens favors, especially in multi-transfused patients, the occurrence of autoimmunization and alloimmunization with the risk of hemolytic transfusion reactions. Thus, this study aimed to determine the rates of alloimmunization and autoimmunization in these individuals, as well as the types of all
Hematol., Transfus. Cell Ther.. Publicado em: 2018-06
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3. Transfusion of older red blood cell units, cytokine burst and alloimmunization: a case-control study
BACKGROUND: Experimental data have shown that the transfusion of older red blood cell units causes alloimmunization, but the clinical applicability of this statement has never been properly assessed in non-sickle cell patients. It has been hypothesized that older units have higher numbers of cytokines, increasing the risk of alloimmunization related to antig
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-10
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4. Red blood cell and leukocyte alloimmunization in patients awaiting kidney transplantation
Objective: To determine the rates of red blood cell and leukocyte alloimmunization in patients with chronic kidney disease awaiting kidney transplantation. Methods: In this cross-sectional and prospective study, the serum of 393 chronic kidney
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013-06
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5. Study of possible clinical and laboratory predictors of alloimmunization against red blood cell antigens in cancer patients
Background: The inflammatory background of patients influences the process of alloimmunization against red blood cell antigens. Proof of this statement to clinical practice is still lacking. Objective: The aim of this study was to verify whether factors related to disease severity and inflammatory status of cancer patients can predict alloimmunization.
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
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6. Molecular matching of red blood cells is superior to serological matching in sickle cell disease patients
OBJECTIVE: To evaluate the usefulness of DNA methods to provide a means to precisely genotypically match donor blood units for the antigen-negative type of 35 sickle cell disease patients<. METHODS: Red blood cell units were investigated for ABO, D, C, c, E, e, K, Fyª, Fy b, Jkª, Jk b, S, s, Diª and RH variants by performing a molecular array (Human Eryth
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
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7. Predição da hemólise fetal em gestantes aloimunizadas / Prediction of fetal hemolysis in alloimmunized pregnancies
OBJETIVO: O objetivo deste estudo foi avaliar fatores clínicos, laboratoriais, dopplervelocimétricos e hematimétricos preditivos da velocidade de hemólise entre a primeira e a segunda transfusões intrauterinas em gestantes aloimunizadas. MÉTODOS: Este estudo retrospectivo compreendeu gestações únicas, com fetos não hidrópicos, submetidos à primei
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/06/2011
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8. Identification of platelet refractoriness in oncohematologic patients
OBJECTIVES: To identify the occurrence and the causes of platelet refractoriness in oncohematologic patients. INTRODUCTION: Platelet refractoriness (unsatisfactory post-transfusion platelet increment) is a severe problem that impairs the treatment of oncohematologic patients and is not routinely investigated in most Brazilian services. METHODS: Forty-four ep
Clinics. Publicado em: 2011
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9. Polimorfismo do gene RHD em indivíduos com fenótipo RhD (RH1) negativo e portadores de aloanticorpo anti-D. / RHD GENE POLYMORPHISMS IN ALLOIMMUNIZED RhD NEGATIVE INDIVIDUALS
O fenótipo RhD negativo é decorrente da deleção total do gene RHD na quase totalidade dos caucasianos, por volta de 20% dos africanos e em 70% dos asiáticos. Em africanos, o RHDΨ caracterizado por uma inserção de 37 pb no exon 4 é um dos principais responsáveis pelo fenótipo RhD negativo. Em asiáticos, o DEL é uma importante causa de RhD neg
Publicado em: 2010
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10. Transfusão de plaquetas: do empirismo ao embasamento científico
Despite major advances in Brazilian blood transfusion therapy with a growing number of scientific publications, an increased number of repeat donors and a decline in serological ineligibility, a lack of conformity in the application of pre-transfusion tests that may compromise transfusion safety is still observed at transfusion agencies in the fringes of the
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2010
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11. Risk factors for alloimmunization by patients with sickle cell disease
Blood transfusion in patients with sickle cell disease (SCD) is limited by the development of alloantibodies to erythrocytes. In the present study, the frequency and risk factors for alloimmunization were determined. Transfusion records and medical charts of 828 SCD patients who had been transfused and followed at the Belo Horizonte Blood Center, Belo Horizo
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-05
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12. Genotipagem RHD fetal atraves da analise do plasma materno
Hemolytic Disease of the Fetus and Newborn still contributes to perinatal morbidity and mortality, in spite of the widespread munoprophylaxis. Prenatal identification of fetal RHD status is a goal of obstetrical practice, in order to prevent maternal immunization and to help in the management of alloimmunized pregnant women. The analysis of the maternal plas
Publicado em: 2004