Active Dendrite
Mostrando 1-12 de 17 artigos, teses e dissertações.
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1. ComputaÃÃo dendrÃtica: uma abordagem de fÃsica estatÃstica
No campo da neurociÃncia computacional, a atividade elÃtrica dos neurÃnios à tradicionalmente modelada por equaÃÃes diferenciais nÃo-lineares acopladas, representando a evoluÃÃo do potencial de membrana e certas variÃveis relacionadas Ãs condutÃncias iÃnicas presentes no sistema. Uma tendÃncia recente consiste na extensÃo desta estratÃgia de
Publicado em: 2007
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2. Chacacterization, modeling and computacional simulation on dynamics of neural cells connections and growth / Caracterização, modelagem e simulação matemático-computacional da dinâmica do crescimento e conexões de células neurais
In this thesis we report the investigation and simulation of dynamic models of neural growing, and their characterization using shape features, considering the form function relationship and neuromorphometry. The thesis begins by presenting an overview about neuroscience, neural cell biology and the biological factors that affects the neuron form development
Publicado em: 2003
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3. Inhibition of Rho Is Required for cAMP-induced Melanoma Cell Differentiation
Up-regulation of the cAMP pathway by forskolin or α-melanocyte stimulating hormone induces melanocyte and melanoma cell differentiation characterized by stimulation of melanin synthesis and dendrite development. Here we show that forskolin-induced dendricity is associated to a disassembly of actin stress fibers. Since Rho controls actin organization, we stu
The American Society for Cell Biology.
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4. Genes regulating dendritic outgrowth, branching, and routing in Drosophila
Signaling between neurons requires highly specialized subcellular structures, including dendrites and axons. Dendrites exhibit diverse morphologies yet little is known about the mechanisms controlling dendrite formation in vivo. We have developed methods to visualize the stereotyped dendritic morphogenesis in living Drosophila embryos. Dendrite development i
Cold Spring Harbor Laboratory Press.
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5. Plexin-B1 is a GTPase activating protein for M-Ras, remodelling dendrite morphology
Plexins are receptors for axonal guidance molecules known as semaphorins. We recently reported that the semaphorin 4D (Sema4D) receptor, Plexin-B1, induces axonal growth cone collapse by functioning as an R-Ras GTPase activating protein (GAP). Here, we report that Plexin-B1 shows GAP activity for M-Ras, another member of the Ras family of GTPases. In cortica
Nature Publishing Group.
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6. On the site of impulse initiation in a neurone.
In the preceding paper (Moore & Westerfield, 1983) the effects of changes in membrane properties and non-uniform geometry on impulse propagation and threshold parameters were investigated. In this paper the contributions of these and other parameters to the site of initiation of an impulse were determined by computer simulations using the Hodgkin-Huxley memb
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7. Spatial integration of local transmitter responses in motoneurones of the turtle spinal cord in vitro.
1. Integration of responses to local activation of transmitter receptors in the dendrites of motoneurones was investigated in a slice preparation of the turtle spinal cord. Membrane-active substances were applied from up to three independent iontophoresis electrodes during intracellular recording from the cell body. 2. Responses to glutamate could be evoked
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8. Effects of electric fields on transmembrane potential and excitability of turtle cerebellar Purkinje cells in vitro.
1. Transmembrane potential (TMP) responses of Purkinje cells (PCs) in isolated turtle cerebellum to externally applied quasi-steady-state electric fields aligned with the dendritic axis were continuously measured using simultaneous intracellular and extracellular recording. TMP was obtained by subtraction of extracellular voltage fields from intracellular po
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9. Sodium channels in dendrites of rat cortical pyramidal neurons.
The voltage-dependent properties that have been directly demonstrated in Purkinje cell and hippocampal pyramidal cell dendrites play an important role in the integrative capacities of these neurons. By contrast, the properties of neocortical pyramidal cell dendritic membranes have been more difficult to assess. Active dendritic conductances near sites of syn
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10. Time-restricted role for dendritic activation of the mTOR-p70S6K pathway in the induction of late-phase long-term potentiation in the CA1
Mammalian target of rapamycin (mTOR) is a key regulator of translational capacity. The mTOR inhibitor rapamycin can prevent forms of protein synthesis-dependent synaptic plasticity such as long-term facilitation in Aplysia and late-phase long-term potentiation (L-LTP) in the hippocampal CA1 region of rodents. In the latter model, two issues remain to be addr
National Academy of Sciences.
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11. Tetrodotoxin-sensitive dendritic spiking and control of axonal firing in a lobster mechanoreceptor neurone.
1. A primary mechanosensory neurone, the anterior gastric receptor (AGR) associated with gastric mill muscle in the lobster foregut was examined in vitro with extra- and intra-cellular recording techniques to understand processes of dendritic integration and dendro-axonal communication. 2. AGR has a 'T'-shaped geometry; its two long (> 3 mm) primary dendrite
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12. The Electrotonic Structure of Pyramidal Neurons Contributing to Prefrontal Cortical Circuits in Macaque Monkeys Is Significantly Altered in Aging
Whereas neuronal numbers are largely preserved in normal aging, subtle morphological changes occur in dendrites and spines, whose electrotonic consequences remain unexplored. We examined age-related morphological alterations in 2 types of pyramidal neurons contributing to working memory circuits in the macaque prefrontal cortex (PFC): neurons in the superior
Oxford University Press.