Abc Transporter
Mostrando 1-12 de 349 artigos, teses e dissertações.
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1. Determination of multidrug resistance mechanisms in Clostridium perfringens type A isolates using RNA sequencing and 2D-electrophoresis
In this study, we screened differentially expressed genes in a multidrug-resistant isolate strain of Clostridium perfringens by RNA sequencing. We also separated and identified differentially expressed proteins (DEPs) in the isolate strain by two-dimensional electrophoresis (2-DE) and mass spectrometry (MS). The RNA sequencing results showed that, compared w
Braz J Med Biol Res. Publicado em: 11/06/2018
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2. Characterisation of an ABC transporter of a resistant Candida glabrata clinical isolate
BACKGROUND Candida glabrata ranks second in epidemiological surveillance studies, and is considered one of the main human yeast pathogens. Treatment of Candida infections represents a contemporary public health problem due to the limited availability of an antifungal arsenal, toxicity effects and increasing cases of resistance. C. glabrata presents intrinsi
Mem. Inst. Oswaldo Cruz. Publicado em: 05/02/2018
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3. Comparative transcriptome profile of the leaf elongation zone of wild barley (Hordeum spontaneum) eibi1 mutant and its isogenic wild type
Abstract The naturally occurring wild barley mutant eibi1/hvabcg31 suffers from severe water loss due to the permeable leaf cuticle. Eibi1/HvABCG31 encodes a full ATP-binding cassette (ABC) transporter, HvABCG31, playing a role in cutin deposition in the elongation zone of growing barley leaves. The eibi1 allele has pleiotropic effects on the appearance of l
Genet. Mol. Biol.. Publicado em: 23/10/2017
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4. A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole
Benznidazole (BZ) is one of the two drugs used for Chagas disease treatment. Nevertheless therapeutic failures of BZ have been reported, which were mostly attributed to variable drug susceptibility among Trypanosoma cruzi strains. ATP-binding cassette (ABC) transporters are involved in a variety of translocation processes and some members have been implicate
Mem. Inst. Oswaldo Cruz. Publicado em: 28/04/2015
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5. Evaluation of the role of ATP-binding cassette transporters as a defence mechanism against temephos in populations of Aedes aegypti
The role of ATP-binding cassette (ABC) transporters in the efflux of the insecticide, temephos, was assessed in the larvae of Aedes aegypti. Bioassays were conducted using mosquito populations that were either susceptible or resistant to temephos by exposure to insecticide alone or in combination with sublethal doses of the ABC transporter inhibitor, verapam
Mem. Inst. Oswaldo Cruz. Publicado em: 2014-11
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6. Transportador ABC e resistência a benznidazol em Trypanosoma cruzi. / ABC transporter and benznidazole resistance in Trypanosoma cruzi.
Ensaios clínicos indicam haver diferenças regionais na eficácia do tratamento da doença de Chagas com (BZ) e Nifurtimox (NFX). Transportadores ABC desempenham um papel importante na resistência a drogas. Evidências indicam que o transportador TcABCG1 é superexpresso em cepas resistentes a BZ. O objetivo geral foi obter evidências para o envolvimento
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/11/2011
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7. Estudos estruturais e funcionais das enzimas SsuD e SsuE do sistema de transporte do tipo ABC de alcano sulfonatos e da proteína ligadora periplasmática PbP da bactéria Xanthomonas axonopodis pv.citri / Structural and funcional studies of the enzymes SsuD and SsuE from the alkanesulphonate ABC transporter and the periplasmic binding protein (PbP) from Xanthomonas axopodis pv.citri
A captação de sulfato em Escherichia coli é dependente do transportador do tipo ABC (do inglês, ATP Binding Cassete), SbpCysAWD, pertencente a um regulon que envolve 26 genes. Na ausência de sulfato, a bactéria induz a expressão de dois outros transportadores ABC, o de proteínas do sistema de transporte de alcanosulfonatos (SsuABCDE) e de sulfonatos
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/01/2011
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8. Inhibition of Saccharomyces cerevisiae Pdr5p by a natural compound extracted from Brazilian Red Propolis
Multidrug resistance of cancer cells and pathogenic microorganisms leading to the treatment failure of some forms of cancer or life-threatening bacterial or fungal infections is often caused by the overexpression of multidrug efflux pumps belonging to the ATP-binding cassette transporters superfamily. The multidrug resistance of fungal cells often involves t
Revista Brasileira de Farmacognosia. Publicado em: 12/08/2011
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9. Avaliação dos efeitos da fertilização nitrogenada (uréiae uréia com NBPT) e do Fungicida maxim - XL na produção de fumonisinas por Fusarium verticillioides
Corn is an economically important cereal worldwide, but it is susceptible to toxigenic fungi contamination, mainly Fusarium verticillioides. This fungus produces fumonisins, which cause several mycotoxicoses and probably esophageal cancer in humans. Due to the problems caused by F. verticillioides and fumonisin contamination in corn, during its cultivation s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2009
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10. Identificação e caracterização dos genes abcCl1 e cypCl1 que codificam um transportador ABC e um citocromo P450 no fitopatógeno Colletotrichum lindemuthianum / Identification and characterization of the genes abcCl1 and cypCl1 that codify an ABC transporter and a cytochrome P450 in phytopathogen Colletotrichum lindemuthianum
Para se defenderem de fungos fitopatogênicos, as plantas produzem proteínas antifúngicas e antibióticos especializados (fitoanticipinas e fitoalexinas). Somente patógenos que conseguem evitar estas respostas defensivas da planta nos estágios iniciais da infecção são capazes de causar doença. O fungo Colletotrichum lindemuthianum (Sacc. &Magnus) Bri
Publicado em: 2009
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11. Molecular and structural analysis of maltose binding protein (MalE) of Xanthomonas axonopodis pv citri. / Análise molecular e estrutural da proteína ligadora de maltose (MalE) de Xanthomonas axonopodis pv. citri.
Maltose uptake in bacteria is mediated by an ABC transporter comprising a substrate binding protein (MalE), two transmembrane proteins, and one ATPase. In the present study, we describe the cloning, expression and biochemical as well as structural analyses of the MalE protein of the phytopagen Xanthomonas axonopodis pv citri (Xac). The malE gene of Xac was c
Publicado em: 2009
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12. Expression, purification and DNA-binding activities of two putative ModE proteins of Herbaspirillum seropedicae (Burkholderiales, Oxalobacteraceae)
In prokaryotes molybdenum is taken up by a high-affinity ABC-type transporter system encoded by the modABC genes. The endophyte β-Proteobacterium Herbaspirillum seropedicae has two modABC gene clusters and two genes encoding putative Mo-dependent regulator proteins (ModE1 and ModE2). Analysis of the amino acid sequence of the ModE1 protein of H. seropedicae
Genetics and Molecular Biology. Publicado em: 2008