5hiaa
Mostrando 13-24 de 64 artigos, teses e dissertações.
-
13. Aspectos do envelhecimento cerebral e função cognitiva em modelo experimental animal e estudo de mecanismos de neurodegeneração em cultura celular
The two phenomena, biological and behavioural, approached in the present work are brain aging and spatial memory. Several studies, comparative and experimental, have shown that aged subjects present significantly impaired performances in different types of cognitive tasks. It is also known that contradictions in literature exist in relation to consequences o
Publicado em: 2007
-
14. Estudo farmacológico e neuroquímico da fase aguda do processo convulsivo induzido por pilocarpina em áreas cerebrais de ratos adultos / Pilocarpine-induced convulsive process investigation in brain areas of adult rats: a neurochemical study
Neste trabalho, estudos comportamentais, farmacológicos e neuroquímicos em áreas cerebrais foram realizados em animais adultos (2 meses de idade) que apresentaram convulsão e estado epiléptico (EP), através da administração de pilocarpina 400mg/kg, s.c., P400, com a finalidade de investigar os mecanismos envolvidos durante a fase aguda (1 e 24h) do p
Publicado em: 2006
-
15. Síndrome carcinóide: diagnóstico e manejo clínico
Carcinóides gastro-intestinais são tumores de crescimento lento originários das células enterocromafínicas ou de Kulchitsky. Sua apresentação clínica depende das combinações de substâncias bioativas que são secretadas. Carcinóides de intestino delgado podem se apresentar com síndrome carcinóide na presença de metástases hepáticas. A manifes
Arquivos Brasileiros de Endocrinologia & Metabologia. Publicado em: 2005-10
-
16. Studies of seizures and actions of nimodipine on pilocarpine-induced seizures in young rats. / Estudo do processo convulsivo e das ações da nimodipina no modelo de convulsão com pilocarpina em ratos jovens
Behavioral and neurochemical studies were carried out with 21 days-old rats pretreated or not with nimodipine (10 or 30mg/Kg, i.p.) on pilocarpine-induced seizures (400mg/Kg, s.c.) to investigate the mechanism involved in the acute phase of seizures and the effects of nimodipine on seizures. The behavioral studies showed peripheral cholinergic signs, stereot
Publicado em: 2005
-
17. Solanum lycocarpum St. Hil unripe fruit effects in pregnant rats and offspring: alterations in reproductive and central monoaminergic systems / Efeitos dos frutos da Solanum lycocarpum St. Hil. em ratas prenhes e sua prole durante a gestação e início da lactação: alterações na esfera reprodutiva e na atividade dos sistemas monoaminérgicos centrais
A Solanum lycocarpum St. Hil (Solanaceae) é uma planta nativa do cerrado brasileiro, cujos frutos possuem os glicoalcalóides esteroidais solasonina e solamargina. É possível que a ingestão de frutos que contenham esses glicoalcalóides possam interferir no equilíbrio do sistema endócrino. O presente estudo foi realizado com o objetivo de avaliar os po
Publicado em: 2005
-
18. Pharmacological study and neurochemical alterations in striatum and prefrontal cortex of mice after convulsions and death induced by cocaine overdose / Estudo farmacológico e de alterações neuroquímicas em córtex pré-frontal e corpo estriado de camundongos após convulsões e morte induzidas por overdose de cocaína
Convulsões e morte são as principais conseqüências relacionadas à overdose de cocaína (COC). Para determinar os sistemas neurotransmissores envolvidos com as convulsões induzidas pela droga camundongos Swiss machos (20-30 g), foram pré-tratados (i.p.) 15, 30 ou 60 min antes da administração de COC 90 mg/kg com drogas que interferem com vários sist
Publicado em: 2005
-
19. Effects of chronic ethanol treatment on monoamine levels in rat hippocampus and striatum
We studied the effects of ethanol on concentrations of noradrenaline (NE), dopamine (DA) and serotonin (5-HT) and their metabolites in rat hippocampus and striatum. Ethanol (2 or 4 g/kg, po, from a 20% aqueous solution) was administered daily to male Wistar rats (4-13 per group) for 30 days and animals were sacrificed 30 min or 48 h after the last administra
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-12
-
20. Leptin increases serotonin turnover by inhibition of brain nitric oxide synthesis
Leptin administration inhibits diencephalic nitric oxide synthase (NOS) activity and increases brain serotonin (5-HT) metabolism in mice. We evaluated food intake, body-weight gain, diencephalic NOS activity, and diencephalic content of tryptophan (TRP), 5-HT, hydroxyindoleacetic acid (5-HIAA), and 5-HIAA/5-HT ratio after intracerebroventricular (ICV) or int
American Society for Clinical Investigation.
-
21. Thiamine deficiency and cerebrospinal fluid 5-hydroxyindoleacetic acid: a preliminary study.
In three out of five patients with low cerebrospinal fluid thiamine concentrations, the 5-hydroxyindoleacetic acid (5HIAA) values also were low. All patients received thiamine replacement therapy; they underwent a second lumbar puncture after 13, 6, 7, 5 and 45 days of treatment. In all patients blood and cerebrospinal fluid thiamine values rose after treatm
-
22. Amine metabolites in the cerebrospinal fluid in Huntington's chorea
The amine metabolites HVA and 5-HIAA in the lumbar CSF of 15 patients with Huntington's chorea were determined. A negative correlation was found between the severity of symptoms and the CSF HVA, but not 5-HIAA levels. The mean HVA concentration was lower than that of a group of patients with miscellaneous neurological disorders, similar to that of a group wi
-
23. Biochemical aspects of Huntington's chorea.
Fifteen patients affected by Huntington's chorea were divided into two groups, 'slow' and 'fast', according to IQ scores on the Wechsler-Bellevue scale, and scores on some motor performance tests. A possible correlation was looked for between some biochemical data (cerebrospinal fluid (CSF), homovanillic acid (HVA), and 5-hydroxyindolacetic acid (5HIAA) leve
-
24. Sites of origin in the central nervous system of monoamine metabolites measured in human cerebrospinal fluid1
The concentrations of homovanillic acid (HVA) and 5-hydroxyindole-acetic acid (5-HIAA) were measured in five cases with partial or complete block of CSF circulation, at various levels. Determinations were made in both a lumbar and a cisternal, or `mixed', sample obtained during pneumoencephalography. Most of the HVA appears to enter the ventricular system at