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1. 1,2,4-oxadiazÃis: sÃntese, desenvolvimento de novas metodologias sintÃticas e avaliaÃÃo da atividade antiinflamatÃria
This work describes the obtainment of many novel 3,5-disubstituted 1,2,4-oxadiazoles. First, the synthesis of ten previously unknown 3-aryl-5-tridecyl- and 3-aryl-5-heptadecyl-1,2,4- oxadiazoles 40a-g, 40h-j, starting from arylamidoximes 12a-g and tetradecanoic as well as heptadecanoic acids 38a and 38b is reported. Second, seven new 3-aryl-5-(cis-heptadec-1
Publicado em: 2007