1k 1c Hypertension
Mostrando 1-12 de 70 artigos, teses e dissertações.
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1. Environmental Enrichment Promotes Antioxidant Effect in the Ventrolateral Medulla and Kidney of Renovascular Hypertensive Rats
Resumo Fundamento: A hipertensão arterial é um precursor para o desenvolvimento da insuficiência cardíaca e renal e, além disso, está associada com o aumento dos marcadores oxidativos. O enriquecimento ambiental dos roedores melhora o desempenho em tarefas de memória, e também parece ter um efeito antioxidante sobre o hipocampo dos ratos normotensos
Arq. Bras. Cardiol.. Publicado em: 02/09/2019
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2. COMPARISON OF DIFFERENT CRITERIA IN THE PREVALENCE OF METABOLIC SYNDROME IN STUDENTS FROM PARANAVAÍ, PARANÁ
RESUMO Objetivo: Investigar a diferença na proporção de escolares com síndrome metabólica diagnosticada segundo diferentes critérios. Métodos: Duzentos e quarenta e um escolares (136 meninos e 105meninas), com idade entre dez e 14 anos, das redes pública e privada de Paranavaí, Paraná. Foram utilizados três diferentes critérios para o diagnó
Rev. paul. pediatr.. Publicado em: 03/06/2019
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3. Familial history of hypertension-induced impairment on heart rate variability was not observed in strength-trained subjects
Family history of hypertension is an important predictive factor for hypertension and is associated with hemodynamic and autonomic abnormalities. Previous studies reported that strength training might reduce arterial blood pressure (AP), as well as improve heart rate variability (HRV). However, the benefits of strength training in the offspring of hypertensi
Braz J Med Biol Res. Publicado em: 14/11/2018
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4. Renovascular hypertension increases serum TNF and CX3CL1 in experimental Trypanosoma cruzi infection
Trypanosoma cruzi triggers a progressive inflammatory response affecting cardiovascular functions in humans and experimental models. Angiotensin II, a key effector of the renin-angiotensin system, plays roles in mediating hypertension, heart failure, and inflammatory responses. T. cruzi and AngII can induce inflammatory responses by releasing inflammatory me
Braz J Med Biol Res. Publicado em: 26/03/2018
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5. UPLC/Q-TOF-MS profiling of phenolics from Canarium pimela leaves and its vasorelaxant and antioxidant activities
ABSTRACT Canarium pimela K.D. Koenig, Burseraceae, have a long history of use in the Chinese traditional medicine treatment of various ailments including hypertension, and our research team has reported the anti-hypertensive activity and delineated the mechanism involved in the action. The following research aims to evaluate the vasorelaxant and antioxidant
Rev. bras. farmacogn.. Publicado em: 2017-12
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6. Possible mechanisms involved in the vasorelaxant effect produced by clobenzorex in aortic segments of rats
Clobenzorex is a metabolic precursor of amphetamine indicated for the treatment of obesity. Amphetamines have been involved with cardiovascular side effects such as hypertension and pulmonary arterial hypertension. The aim of the present study was to investigate whether the direct application of 10–9–10–5 M clobenzorex on isolated phenylephrine-precont
Braz J Med Biol Res. Publicado em: 07/08/2017
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7. Flax lignan concentrate attenuate hypertension and abnormal left ventricular contractility via modulation of endogenous biomarkers in two-kidney-one-clip (2K1C) hypertensive rats
ABSTRACT The present investigation was designed to study the effect of flax lignan concentrate obtained from Linum usitatissimum L., Linaceae, in two-kidney, one clip (2K1C) hypertension model in Wistar rats. 2K1C Goldblatt model rats were divided randomly into six groups: sham, 2K1C control, captopril (30 mg/kg), flax lignan concentrate (200, 400 and 800 mg
Rev. bras. farmacogn.. Publicado em: 2016-10
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8. Time-course effects of aerobic exercise training on cardiovascular and renal parameters in 2K1C renovascular hypertensive rats
Exercise training (Ex) has been recommended for its beneficial effects in hypertensive states. The present study evaluated the time-course effects of Ex without workload on mean arterial pressure (MAP), reflex bradycardia, cardiac and renal histology, and oxidative stress in two-kidney, one-clip (2K1C) hypertensive rats. Male Fischer rats (10 weeks old; 150�
Braz J Med Biol Res. Publicado em: 11/08/2015
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9. Combined aliskiren and L-arginine treatment has antihypertensive effects and prevents vascular endothelial dysfunction in a model of renovascular hypertension
Angiotensin II is a key player in the pathogenesis of renovascular hypertension, a condition associated with endothelial dysfunction. We investigated aliskiren (ALSK) and L-arginine treatment both alone and in combination on blood pressure (BP), and vascular reactivity in aortic rings. Hypertension was induced in 40 male Wistar rats by clipping the left rena
Braz J Med Biol Res. Publicado em: 24/10/2014
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10. Bases moleculares da microalbuminúria associada à hipertensão arterial essencial: papel da reabsorção tubular de albumina / Molecular basis of microalbuminuria in essential hypertension: role of tubular albumin reabsorption
Evidências epidemiológicas indicam que a presença de microalbuminúria prediz maior freqüência de eventos cardiovasculares e mortalidade em hipertensos essenciais. A microalbuminúria pode ser decorrente do aumento da permeabilidade glomerular e/ou da diminuição da reabsorção desta macromolécula no túbulo proximal. Todavia não é sabido se os mec
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/10/2012
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11. Avaliação dos efeitos da injeção intravascular de drogas vasoconstritoras, presentes nas soluções anestésicas locais, sobre a pressão arterial e glicemia de ratos normotensos, diabéticos, hipertensos renais um-rim, um clip (1R-1C) e 1R / Blood pressure and glycemic evaluation levels after intravenous injection of adrenaline and felypressin in normotensive, diabetic, 1K-1C hypertensive and 1K-1C hypertensive-diabetic rats
O presente trabalho teve como objetivo associar modelos indutivos de diabetes e hipertensão, analisar e comparar o efeito de agentes vasoconstritores presentes nas soluções anestésicas locais, injetados por via intravenosa nas doses de 80, 160, 320, 640 e 1280ng (adrenalina) ou 0,125; 0,25; 0,5; 1; 2 e 3 x10-3UI (felipressina), sobre a pressão arterial
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/03/2012
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12. Allicin, a SUR2 opener: possible mechanism for the treatment of diabetic hypertension in rats
The garlic (Allium sativum L., Amaryllidaceae) has been popularly used in the treatment of diabetes and cardiac complications. In the present work, we have studied the possible mechanisms, sulfonylurea receptor (SUR) selectivity of allicin in diabetic hypertensive rats. Diabetic hypertension was induced by intraperitoneal injection of streptozotocin (50 mg/k
Rev. bras. farmacogn.. Publicado em: 12/04/2012